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MYP_162964
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Basic Information
Mastoparan-C [L1G, L7A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C65H120N18O16
Standard
Sequence
GNLKALAAVAKKIL
Physicochemical Analysis
1409.76 Da
10.30
2.76
2.55
0.1969
0.84
0.58
0.24
4.85
160.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.77
-3.49
19.0
19.0
50.0
99.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140131 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
64 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0194978 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 700603
128 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0265038 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
128 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0294047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
256 μM
Hemolysis
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0313339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
64 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
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