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MYP_162956
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
55 amino acids
C272H439N69O83S7
Standard
Sequence
MENEKYLQVVEDEELEQLVGGIGPGWVETITKDCPWKMPVACVTIMGQTICKKCR
Physicochemical Analysis
6228.26 Da
4.69
-3.52
-3.82
-0.0641
-0.18
0.45
0.05
52.63
83.09
0.0545
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2441.14
-18.99
85.0
87.0
209.0
431.0
8.0
58.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0331175 VERIFIED: NO
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Lantibiotic
Structure & Mods
thioether-cyclized lantibiotic scaffold [Cyclic]
post-translationally modified ribosomal peptide [Modified]
Lanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A853T853/entry
RECORD: Rec_0367975 VERIFIED: NO
Provenance & Taxonomy
Bacillus cereus F65185 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID22645259 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22645259/; https://www.uniprot.org/uniprotkb/C2XEG1/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0405531 VERIFIED: NO
Provenance & Taxonomy
Bacillus sp. BI3 [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2N3NP21/entry