MYP_162936
Basic Information
Lysozyme
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antifungal
Binding / Molecular interaction Binding activity
Binding / Molecular interaction Metal-binding peptide
Standard
130 amino acids
C633H992N200O186S10
Standard
Sequence
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
Physicochemical Analysis
14700.53 Da
9.28
7.77
7.38
0.0598
-0.49
0.79
-0.12
32.13
69.85
0.1000
36440.00
36940.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
6347.62
-71.69
234.0
205.0
484.0
1029.0
21.0
145.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084303 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0258083 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-lactalbumin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Lactose Synthesis Cell Wall Remodeling Calcium Binding Antimicrobial
RECORD: Rec_0306968 VERIFIED: NO
Provenance & Taxonomy
Gorilla gorilla gorilla [Animal]
9595
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0382861 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
You can rotate, zoom, and view the crystal structure here in the PDB. Synergy:AMPs: It showed synergistic effect with LL-37 (Abou Aliwa et al., 2014). Pathogen infection strategy: Mycobacterium tuberculosis uses a novel glycosylated and surface-localized lipoprotein, LprI, to abrogate the lytic activity of lysozyme (Sethi D eta l., 2016). AMPs in use: food preservation: lysozyme is used as Japan's most trusted preservative for fruits, vegetables, and food (https://www.bioseutica.com/products/lysozyme). Updated 2/2016; Jan2017; 8/2021 GW
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive
RECORD: Rec_0418873 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial