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MYP_162919
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Basic Information
Parkerin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C85H141N25O25S
Standard
Sequence
GWANTLKNVAGGLCKITGAA
Physicochemical Analysis
1945.25 Da
9.31
1.75
1.53
0.0874
0.36
0.56
0.27
-6.90
93.00
0.0500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
810.69
-9.57
29.0
28.0
63.0
136.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005857 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
Staphylococcus aureus ATCC 2592
37.5 μg/mL
MIC
PaperNovel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri
RECORD: Rec_0045363 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20153801/ PMID20153801 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20153801/
RECORD: Rec_0065881 VERIFIED: YES
Provenance & Taxonomy
Xizang plateau [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20467242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20467242/
RECORD: Rec_0136278 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Parkerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
19.28 μM
MIC
PaperZ. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri Evidence URLhttps://www.uniprot.org/uniprotkb/D0ES75/entry
RECORD: Rec_0147318 VERIFIED: YES
Provenance & Taxonomy
Nanorana parkeri [Animal]
Parkerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
51.4 μM
MIC
PaperZ. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri Evidence URLhttps://www.uniprot.org/uniprotkb/D0ES75/entry
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