Peptide Database

Peptide NameP5(ACE2 (4-39))

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC192H275N47O67

DescriptionStandard

        EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEE
    

Molecular Weight4313.51 Da

Isoelectric Point (pI)4.29

Net Charge (pH 7.0)-6.06

Net Charge (pH 7.4) -6.30

Charge Density (pH 7.0) -0.1683

GRAVY Index-1.06

Hydrophobic Moment 0.54

Boman Index-0.11

Instability Index80.66

Aliphatic Index 51.67

Aromaticity 0.1667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1897.11

LogP -19.53

H-bond Donors 63.0

H-bond Acceptors 62.0

Rotatable Bonds 143.0

Heavy Atoms 306.0

Ring Count 8.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354819 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyACE2-derived peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetSevere acute respiratory syndrome coronavirus

Activity6 μM

MethodIC50

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