Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC148H249N45O44S4

DescriptionStandard

        TLQKYYCRVRGGRCAVLSCLPKEEQIGKCST
    

Molecular Weight3491.10 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)3.36

Net Charge (pH 7.4) 3.10

Charge Density (pH 7.0) 0.1084

GRAVY Index-0.37

Hydrophobic Moment 0.42

Boman Index-0.17

Instability Index62.35

Aliphatic Index 72.26

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1473.45

LogP -16.34

H-bond Donors 57.0

H-bond Acceptors 52.0

Rotatable Bonds 118.0

Heavy Atoms 241.0

Ring Count 3.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099210 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)