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MYP_162862
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C91H157N23O23
Standard
Sequence
GIVDFAKGVLGKIKNVLGI
Physicochemical Analysis
1941.36 Da
9.70
1.76
1.55
0.0925
0.95
0.49
0.37
-33.68
153.68
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
745.57
-4.15
25.0
25.0
68.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169462 VERIFIED: YES
Provenance & Taxonomy
Floodplain toadlet [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNovel uperin peptides from the dorsal glands of the australian floodplain toadlet Uperoleia inundata.
RECORD: Rec_0190085 VERIFIED: NO
Provenance & Taxonomy
Uperoleia inundata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0245081 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S.uberis
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ637
RECORD: Rec_0279842 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0339423 VERIFIED: NO
Provenance & Taxonomy
Uperoleia inundata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Non-hemolytic Non-ribosomal
Micrococcus luteus
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/P82031/entry; https://bblserver.org.in/ampdb/
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