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MYP_162841
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Basic Information
Casein alpha-s1 [018-033]
Anticancer
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
16 amino acids
C93H132N20O22
Standard
Sequence
ENLLRFFVAPFPEVFG
Physicochemical Analysis
1882.16 Da
4.53
-1.16
-1.33
-0.0725
0.65
0.54
0.35
68.39
91.25
0.2500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
661.83
-1.42
21.0
21.0
55.0
135.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207599 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
250 μM
IC50
RECORD: Rec_0235339 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
250 μM
IC50
PaperIdentification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765. PMID15537298 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15537298/
RECORD: Rec_0272458 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperJuillerat-Jeanneret L., Robert M.-C., Juillerat M. A.. Peptides from Lactobacillus hydrolysates of bovine milk caseins inhibit prolyl-peptidases of human colon cells. J. Agric. Food Chem. 59, 370-377, 2011.
RECORD: Rec_0332189 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
250 μM
IC50
PaperIdentification of Angiotensin-I-Converting Enzyme Inhibitory Peptides Derived from Sodium Caseinate Hydrolysates Produced by Lactobacillus helveticus NCC 2765 | Robert, M-C. et al. | DOI: 10.1021/jf049510t Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0369508 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperIdentification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765 PMID15537298 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15537298/
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