Peptide Database

Peptide NameBrevinin-1DYb (Brevinin-1CDYb)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC355H572N88O99S4

DescriptionStandard

        MFTLKKSLLLLFFLGTISLSLCEEERNAEEERRDYPEERDVEVEKRFLSLALAALPKLFCLIFKKC
    

Molecular Weight7785.13 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0228

GRAVY Index0.05

Hydrophobic Moment 0.56

Boman Index-0.01

Instability Index54.24

Aliphatic Index 109.39

Aromaticity 0.1061

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3035.16

LogP -18.08

H-bond Donors 109.0

H-bond Acceptors 102.0

Rotatable Bonds 269.0

Heavy Atoms 546.0

Ring Count 9.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099249 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0127661 VERIFIED: YES