Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC552H876N150O169S2

DescriptionStandard

        PDLSGYEKSGLGNVNYNISRIHITAVEFPSASISLIPQTGIKLVIENASLTFDTNWNIRTWMFKGNGRSTVYISKVFVTAVFSIPLGNTGHTSISLTSCRTTSGDIDIRLNGKS
    

Molecular Weight12381.89 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.94

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.00

Hydrophobic Moment 0.56

Boman Index0.11

Instability Index22.81

Aliphatic Index 93.16

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5138.70

LogP -59.75

H-bond Donors 184.0

H-bond Acceptors 176.0

Rotatable Bonds 406.0

Heavy Atoms 873.0

Ring Count 18.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136334 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocolius indicus (Red-faced mousebird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria