Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC421H662N108O124S10

DescriptionStandard

        MKILYMLLMFVFSVSCGPSVPQKNTREIAGRKRECYLVRGSCKSECNTWEYVYSYCDTEPCCVVREYQKPIIETTLSKTYTA
    

Molecular Weight9541.06 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.09

Charge Density (pH 7.0) 0.0297

GRAVY Index-0.21

Hydrophobic Moment 0.59

Boman Index-0.03

Instability Index51.86

Aliphatic Index 70.00

Aromaticity 0.1220

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3762.26

LogP -34.24

H-bond Donors 141.0

H-bond Acceptors 137.0

Rotatable Bonds 311.0

Heavy Atoms 663.0

Ring Count 15.0

Amide Bonds 85.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0376113 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence