Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC968H1495N231O302S8

DescriptionStandard

        QIDDLAEVDYSLSGLPAVLQTFIDLDLKGIVFPAGNHTDSPYMAASFTIPDQSDSMLYLAFSEYFFQSSSFAYYTAGAFNMTIAEEVSRTQRNGLRTCSYFNINTEIFSSIIPEVAKYSITPYPVMLKLMSTEIPTISLQQDSFTAEIQGSVEVLAILPDSTTQSLFTLNIAANTSISLNIFDQKLMGLLCLNR
    

Molecular Weight21457.11 Da

Isoelectric Point (pI)4.15

Net Charge (pH 7.0)-12.15

Net Charge (pH 7.4) -12.47

Charge Density (pH 7.0) -0.0626

GRAVY Index0.20

Hydrophobic Moment 0.77

Boman Index0.19

Instability Index55.57

Aliphatic Index 96.08

Aromaticity 0.1134

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8516.62

LogP -105.23

H-bond Donors 292.0

H-bond Acceptors 299.0

Rotatable Bonds 696.0

Heavy Atoms 1509.0

Ring Count 32.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214254 VERIFIED: NO

Provenance & Taxonomy

OrganismMelospiza melodia (Song sparrow) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria