Peptide Database

Peptide NameACE2 (4-26)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC124H178N30O43

DescriptionStandard

        EEQAKTFLDKFNHEAEDLFYQSS
    

Molecular Weight2776.92 Da

Isoelectric Point (pI)4.35

Net Charge (pH 7.0)-4.07

Net Charge (pH 7.4) -4.30

Charge Density (pH 7.0) -0.1769

GRAVY Index-1.15

Hydrophobic Moment 0.54

Boman Index-0.17

Instability Index83.81

Aliphatic Index 42.61

Aromaticity 0.1739

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1218.23

LogP -11.72

H-bond Donors 40.0

H-bond Acceptors 40.0

Rotatable Bonds 94.0

Heavy Atoms 197.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325443 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetSARS-CoV:inhibition of pseudovirus infection in HeLa cells

Activity50 μM

MethodIC50

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