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MYP_162414
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Basic Information
Brevinin-2Va
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
21 amino acids
C103H173N27O29
Standard
Sequence
GIWDTLKNVGKAVLGKVLENV
Physicochemical Analysis
2253.64 Da
8.50
0.76
0.55
0.0362
0.29
0.65
0.19
-21.89
134.29
0.0476
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
920.18
-6.60
31.0
30.0
77.0
159.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009282 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
12.5 μM
MIC
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0010673 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0065185 VERIFIED: YES
Provenance & Taxonomy
Lithobates virgatipes [Animal]
Brevinin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
50.0 μM
MIC
PaperJ.M. Conlon et al. / Regulatory Peptides 131 (2005) 38-45. Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana)
RECORD: Rec_0159570 VERIFIED: NO
Provenance & Taxonomy
Rana virgatipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0163323 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
50 μM
MIC
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
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