Peptide Database

Peptide NamePenaeidin-2a (Pen-2a; shrimps, Arthropods, animals)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC243H382N74O62S6

DescriptionStandard

        YRGGYTGPIPRPPPIGRPPFRPVCNACYRLSVSDARNCCIKFGSCCHLVK
    

Molecular Weight5524.48 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)6.78

Net Charge (pH 7.4) 6.43

Charge Density (pH 7.0) 0.1357

GRAVY Index-0.25

Hydrophobic Moment 0.69

Boman Index-0.05

Instability Index48.89

Aliphatic Index 60.40

Aromaticity 0.1000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2136.11

LogP -22.11

H-bond Donors 80.0

H-bond Acceptors 76.0

Rotatable Bonds 164.0

Heavy Atoms 385.0

Ring Count 14.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414008 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus vannamei [Animal]

FamilyPrAMP

Tax ID6689

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsIt contains a Pro-rich domain from residue 8 to 23. P: 16%

Bio-Activity Profile

Function

Antimicrobial Antifungal Anticancer

TargetE-carotovora

Activity>40 μM

MethodMIC

RECORD: Rec_0415712 VERIFIED: YES