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MYP_162413
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Basic Information
Penaeidin-2a (Pen-2a; shrimps, Arthropods, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
50 amino acids
C243H382N74O62S6
Standard
Sequence
YRGGYTGPIPRPPPIGRPPFRPVCNACYRLSVSDARNCCIKFGSCCHLVK
Physicochemical Analysis
5524.48 Da
9.55
6.78
6.43
0.1357
-0.25
0.69
-0.05
48.89
60.40
0.1000
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2136.11
-22.11
80.0
76.0
164.0
385.0
14.0
51.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261024 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Fusarium oxysporum
PaperPubMed PMID: 11028917 | PubMed PMID: 9353298 | PubMed PMID: 10561573 PMID11028917;9353298;10561573 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11028917/
RECORD: Rec_0268292 VERIFIED: YES
Provenance & Taxonomy
Penaeus vannamei [Animal]
PrAMP
6689
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains a Pro-rich domain from residue 8 to 23. P: 16%
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
yeast C-albicans
>20 μM
MIC
PaperPenaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).
RECORD: Rec_0280504 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 11028917 | PubMed PMID: 9353298 | PubMed PMID: 10561573 PMID11028917;9353298;10561573 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11028917/
RECORD: Rec_0280533 VERIFIED: YES
Provenance & Taxonomy
Penaeus vannamei [Animal]
PrAMP
6689
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
It contains a Pro-rich domain from residue 8 to 23. P: 16%
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
>20 μM
MIC
PaperPenaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).
RECORD: Rec_0328135 VERIFIED: YES
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Penicillamine
Bio-Activity Profile
Antimicrobial
PMID11028917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11028917/
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