Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC858H1370N254O249S10

DescriptionStandard

        MSRKLRYGLSAAVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGAILVDGKPVVPGMKLSKEKCDQVNAIERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQISRRDQESALACWGIDR
    

Molecular Weight19548.26 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.09

Charge Density (pH 7.0) 0.0425

GRAVY Index-0.37

Hydrophobic Moment 0.70

Boman Index-0.06

Instability Index45.85

Aliphatic Index 80.06

Aromaticity 0.0791

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8136.44

LogP -86.57

H-bond Donors 293.0

H-bond Acceptors 268.0

Rotatable Bonds 652.0

Heavy Atoms 1371.0

Ring Count 28.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327483 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O145:H28 [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase

RECORD: Rec_0410049 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage Lyz12581Vzw [Virus]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

MethodQualitative functional evidence