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MYP_162381
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C25H40N6O7
Standard
Sequence
PVPQP
Physicochemical Analysis
536.62 Da
5.96
-0.04
-0.10
-0.0083
-0.82
0.38
0.12
162.08
58.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
191.24
-1.30
5.0
7.0
11.0
38.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004763 VERIFIED: NO
Provenance & Taxonomy
Triticum aestivum [Plant]
ACE-inhibitory peptide
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnalysis of Domains in Selected Plant and Animal Food Proteins - Precursors of Biologically Active Peptides - In Silico Approach
RECORD: Rec_0143512 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
110.0
IC50
PaperKohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.. Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem. 53, 2107-2114 (1989).
RECORD: Rec_0145670 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0263919 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
ACE inhibitory peptide
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
RECORD: Rec_0309971 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
110 μM
IC50
PaperInhibition of angiotensin I-converting enzyme by synthetic peptides of human ?-casein PMID1368548 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368548/
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