Peptide Database

Peptide NameSLAY-screened peptide P5652

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H147N25O28S2

DescriptionStandard

        SDPHLHMFYPAPYLCPNASF
    

Molecular Weight2307.60 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-1.38

Net Charge (pH 7.4) -1.70

Charge Density (pH 7.0) -0.0688

GRAVY Index-0.14

Hydrophobic Moment 0.22

Boman Index0.24

Instability Index60.86

Aliphatic Index 49.00

Aromaticity 0.2000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 799.73

LogP -4.90

H-bond Donors 26.0

H-bond Acceptors 31.0

Rotatable Bonds 61.0

Heavy Atoms 163.0

Ring Count 10.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141840 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/