Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length492 amino acids

Chemical FormulaC2460H3892N648O692S12

DescriptionStandard

        MGVQSLAVACGTLALCLALTTATNPGFVVRITTATNPGFVVRITQAGLDYAHEQGIAILEKKLAQLKLSDISGDSRVLHVGKVHYELSRLRLRDFHLPYTRITPISNVGLQVSISNAFAELDGDWRVKFLFVSRDHGSFNLKVENVYIKIFLSLGSDTTGKPTISTSDCSVRISKVRVLFSGRLGWLYNLFHSVIESRLRKILESKVCDNVAKSVQNELQTYIQTLPVTARINAKIGLDYALVAPPRATAQSLDLYLKGEFYSLAHRSTVPFSPPPLALPPDHDRMVYFGASSYFFNTACIAYHKAGALVFEITEATIPKDVGFKLDTSVFSAFIPQLEEMYPDMPMKFRLSAPTAPFLTIGPGGISFQPVVDAQAYAILPNSSLAPLFLLSLTGNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVQLLQTVMNNLISSTLIPHLNAHLDEGFPLPLLDRIQLSNTLVKFYQNFLMLGADVHFQPQA
    

Molecular Weight54001.92 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.0153

GRAVY Index0.21

Hydrophobic Moment 0.66

Boman Index0.15

Instability Index31.72

Aliphatic Index 106.61

Aromaticity 0.0915

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307122 VERIFIED: NO

Provenance & Taxonomy

OrganismCyanistes caeruleus (Eurasian blue tit) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria