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MYP_162358
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Basic Information
HNH endonuclease
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
238 amino acids
C1191H1823N321O368S2
Standard
Sequence
MVWNSEHNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKSIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDPRDQAGTASGNGSQIETGQKWLDLSVTNNGEGAKIPSNIADKLRGRHYDSFRKSREDLWLEISKDPELSKQFSNGNIEAMQEGKAPTAPFAGHYVGPKQVIKKFEIHHIKPIEEGGGVYDIDNLRITTPKLHKFIHYGE
Physicochemical Analysis
26590.28 Da
5.29
-10.66
-11.42
-0.0448
-0.73
0.64
-0.05
46.73
71.72
0.0882
35410.00
35410.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0063119 VERIFIED: YES
Provenance & Taxonomy
Salmonella enterica subsp. diarizonae serovar 48:i:z [Bacterium]
Pyocin/Colicin
1192842
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal
Escherichia coli
PaperSKESA: strategic k-mer extension for scrupulous assemblies [PMID:30286803] PMID30286803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30286803/
RECORD: Rec_0069160 VERIFIED: YES
Provenance & Taxonomy
Salmonella diarizonae [Bacterium]
Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal
Escherichia coli (Gram-negative)
PaperSKESA: strategic k-mer extension for scrupulous assemblies PMID30286803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30286803/
RECORD: Rec_0141392 VERIFIED: YES
Provenance & Taxonomy
Salmonella enterica [Bacterium]
Pyocin/Colicin
28901
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal
Escherichia coli
PaperSKESA: strategic k-mer extension for scrupulous assemblies [PMID:30286803] PMID30286803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30286803/
RECORD: Rec_0157271 VERIFIED: YES
Provenance & Taxonomy
Salmonella enterica I [Bacterium]
Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal
Escherichia coli (Gram-negative)
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A3V4R338/entry
RECORD: Rec_0173261 VERIFIED: YES
Provenance & Taxonomy
Salmonella enteritidis [Bacterium]
Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal
Escherichia coli (Gram-negative)
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A403FMQ3/entry
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