Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC349H549N95O83S10

DescriptionStandard

        MAPCRKMFYFVIALFFVLAQFPSGEFAVCETCRLGRGKCRKICLESEKIYGNCRLNFFCCRPKILR
    

Molecular Weight7724.33 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)7.43

Net Charge (pH 7.4) 7.08

Charge Density (pH 7.0) 0.1125

GRAVY Index0.30

Hydrophobic Moment 0.66

Boman Index0.04

Instability Index32.72

Aliphatic Index 78.33

Aromaticity 0.1515

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2871.47

LogP -19.43

H-bond Donors 110.0

H-bond Acceptors 101.0

Rotatable Bonds 255.0

Heavy Atoms 537.0

Ring Count 13.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080386 VERIFIED: NO

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence