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MYP_162330
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Basic Information
p2(gag) peptide[Δ10-14,E2A]
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Enzyme modulation ▸ Enzyme inhibition ▸ Maturation inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
9 amino acids
C35H61N11O14S
Standard
Sequence
AAAMSQVTN
Physicochemical Analysis
891.99 Da
5.57
-0.20
-0.39
-0.0227
0.33
0.28
0.19
44.60
65.56
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
422.76
-6.74
14.0
15.0
28.0
61.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022381 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV
HIV | CEM/LAV-1 cells
100 μM
IC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperBlocking of human immunodeficiency virus type-1 virion autolysis by autologous p2(gag) peptide. | Misumi S, Morikawa Y, Tomonaga M, Ohkuma K, Takamune N, Shoji S. | J Biochem. 2004 Mar;135(3):447-53. | DOI:10.1093/jb/mvh052 | PMID:15113844 PMID15113844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113844/
RECORD: Rec_0069165 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID15113844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113844/
RECORD: Rec_0072336 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Maturation inhibitor Protease inhibition
CEM/LAV-1
100 μM
IC50
PaperBlocking of human immunodeficiency virus type-1 virion autolysis by autologous p2(gag) peptide. PMID15113844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113844/
RECORD: Rec_0214949 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID15113844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113844/
RECORD: Rec_0266727 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV:inhibition of protease activity in CEM/LAV-1 cells
100 μM
IC50
PMID15113844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113844/
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