Peptide Database

Peptide NameSLAY-screened peptide P415

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC76H128N18O18S

DescriptionStandard

        RTLPFCAPGIVLTLI
    

Molecular Weight1614.00 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0500

GRAVY Index1.48

Hydrophobic Moment 0.38

Boman Index0.48

Instability Index36.53

Aliphatic Index 156.00

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 555.50

LogP -2.07

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 47.0

Heavy Atoms 113.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023021 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/