Peptide Database

Peptide NamePyrokinin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC47H74N14O11

DescriptionStandard

        HTAGFIPRL
    

Molecular Weight1011.18 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0941

GRAVY Index0.28

Hydrophobic Moment 0.47

Boman Index0.21

Instability Index-11.07

Aliphatic Index 97.78

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 398.14

LogP -2.62

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 29.0

Heavy Atoms 72.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025966 VERIFIED: YES

Provenance & Taxonomy

OrganismPeriplaneta americana [Animal]

FamilyPyrokinin

Tax ID6978

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0093257 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0335903 VERIFIED: YES

Provenance & Taxonomy

OrganismPeriplaneta americana [Animal]

FamilyPyrokinin

Tax ID6978

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0339911 VERIFIED: NO

Provenance & Taxonomy

OrganismPeriplaneta americana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide