Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 2.3

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC177H292N56O50S6

DescriptionStandard

        ITINVKCTSPQQCLRPCKDRFGQHAGGKCINGKCKCYP
    

Molecular Weight4196.95 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.78

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.1522

GRAVY Index-0.57

Hydrophobic Moment 0.53

Boman Index-0.15

Instability Index46.58

Aliphatic Index 51.32

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1729.90

LogP -21.08

H-bond Donors 64.0

H-bond Acceptors 63.0

Rotatable Bonds 139.0

Heavy Atoms 289.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0340936 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides limpidus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Ion channel blocker

TargetInhibitor of voltage-gated potassium