Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length280 amino acids

Chemical FormulaC1404H2248N352O422S6

DescriptionStandard

        MLQTLLADLNTQLKTLKAKVSEYTEIDFSLRSPVVSDNSIEMGLKGVFYNTQQRVEPPSSPPAFSLASQNTNMFYIAVSAFTINSAFLLLHKTNVFNIRITDDMVPSVSPIRLSTTTFGAFIPQISETHPDLKLELKVETVKEPIIKLEQDHVILQLLSTVTAVQSDNTTNTLFVLNLESVASVQVSVEEGDLAFNLTLEKIKGSMNDKPFKVENINFLTVIMHNIVFPIIKAHLAKGLQPPGLLGSYIGKVHIVNPQVKVLNDYVLIGTDIEFEENTSS
    

Molecular Weight31003.36 Da

Isoelectric Point (pI)5.26

Net Charge (pH 7.0)-7.94

Net Charge (pH 7.4) -8.53

Charge Density (pH 7.0) -0.0283

GRAVY Index0.11

Hydrophobic Moment 0.56

Boman Index0.14

Instability Index43.12

Aliphatic Index 109.21

Aromaticity 0.0714

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390112 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria