Peptide Database

Peptide NameSLAY-screened peptide P2913

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H149N25O29S2

DescriptionStandard

        CFLSSLIPSRPSLDIGCAHE
    

Molecular Weight2145.46 Da

Isoelectric Point (pI)5.51

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0582

GRAVY Index0.42

Hydrophobic Moment 0.32

Boman Index0.19

Instability Index51.97

Aliphatic Index 102.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 844.74

LogP -8.86

H-bond Donors 31.0

H-bond Acceptors 31.0

Rotatable Bonds 66.0

Heavy Atoms 149.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162897 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/