Peptide Database

Peptide NameE25A

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Complement inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Complement Pathway

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC123H213N35O43S2

DescriptionStandard

        PAICQRATATLGTVGSNTSGTTEIAACILL
    

Molecular Weight2934.35 Da

Isoelectric Point (pI)6.35

Net Charge (pH 7.0)-0.06

Net Charge (pH 7.4) -0.15

Charge Density (pH 7.0) -0.0019

GRAVY Index0.65

Hydrophobic Moment 0.38

Boman Index0.27

Instability Index36.16

Aliphatic Index 104.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1240.45

LogP -17.79

H-bond Donors 47.0

H-bond Acceptors 45.0

Rotatable Bonds 94.0

Heavy Atoms 203.0

Ring Count 1.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047330 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Complement inhibitor

TargetSheep erythrocytes

Activity770 μM

MethodHemolysis

RECORD: Rec_0271693 VERIFIED: YES