Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length563 amino acids

Chemical FormulaC2690H4247N813O834S24

DescriptionStandard

        MGYRTENYGRGQAFENDKTTTGARCIASIDDSEFDRRIVRVGDMTTPCPKCGERGRIINGESRVEFFGKAVAMDRSEVSCGCPHGTNRVIAPAGQWMGKGRDPVEVAREEHVARVVAEREAEEKRRADEREQNRVFAKSCLRGEGCNDAGEEREPHTNFASMAFYQAVPPADPASDTDVPQHAQTAKKKNPVDDIPKPKKRSALYKWLNGNHEEMDYQAATAAATSAANAQMAVEGASVLGLIGGSAITSGTWAVKLGEMASGLGRIAASGPGAPIAAVVMGMMPGRLNDGEQDFIDRMRLEQMREAPSRVRYTWEQDAKGNPVPHGWHTPPGQDMVRVRKMAWDSSRKAYTFTTEEDPRITIIWTPDSSGVNVPSNTGNQNPVRIPNPVVVDPLPENTSIEATTTPAPEEKNFADYILILPLPNIPPIYVYLRNNPGQVTGNGQKVSGIWLSDANTDNGSPVPSQIADKLRGRTFSNFDQFREAFWSEVSKAPDLSRQFIPNNINRMKNGRAPRSRFIDTVGKRRSFEIHHIKLISQGGEVYNVDNMAITTPKRHIDIHRGK
    

Molecular Weight62090.01 Da

Isoelectric Point (pI)8.07

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 1.48

Charge Density (pH 7.0) 0.0044

GRAVY Index-0.66

Hydrophobic Moment 0.83

Boman Index-0.11

Instability Index41.34

Aliphatic Index 63.62

Aromaticity 0.0657

Extinction Coeff. Reduced 65890.00

Extinction Coeff. Oxidized 66265.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275099 VERIFIED: YES

Provenance & Taxonomy

OrganismRouxiella aceris [Bacterium]

FamilyPyocin/Colicin

Tax ID2703884

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli