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MYP_162154
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Basic Information
A110
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HCMV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
20 amino acids
C104H158N28O31
Standard
Sequence
IEVTFVNRRGDGAELWYLSA
Physicochemical Analysis
2296.54 Da
4.68
-1.23
-1.44
-0.0617
-0.03
0.39
0.08
65.39
97.50
0.1500
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
971.49
-7.74
35.0
30.0
73.0
163.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0086149 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19740994 PMID19740994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19740994/
RECORD: Rec_0150298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Human cytomegalovirus (Replication); HeLa
35 %
GFP assay
PaperInhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84. | Kaiser N, Lischka P, Wagenknecht N, Stamminger T. | J Virol. 2009 | PMID:19740994 PMID19740994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19740994/
RECORD: Rec_0159338 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCMV Replication inhibition
Human cytomegalovirus(HCMV) | HeLa cells
Mammalian: 20 h; Yeast: 30 min; E. coli: >10 h
PaperInhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84. | Kaiser N, Lischka P, Wagenknecht N, Stamminger T. | J Virol. 2009 Nov;83(22):11902-13. | DOI:10.1128/JVI.01378-09 | PMID:19740994 PMID19740994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19740994/
RECORD: Rec_0306122 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
human cytomegalovirus(HCMV):inhibition of virus replication in HeLa cells
35 %
Inhibition
PaperPubMed PMID: 19740994 PMID19740994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19740994/
RECORD: Rec_0410129 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 65.0%, C 35.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/