Peptide Database

Peptide NameCyclic cationic V6 peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC121H167N25O21S2

DescriptionStandard

        CFKFKFKFGSGFKFKFKFC
    

Molecular Weight2371.91 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)5.73

Net Charge (pH 7.4) 5.49

Charge Density (pH 7.0) 0.3018

GRAVY Index0.13

Hydrophobic Moment 0.37

Boman Index0.10

Instability Index-37.99

Aliphatic Index 0.00

Aromaticity 0.4211

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 763.47

LogP -1.04

H-bond Donors 29.0

H-bond Acceptors 29.0

Rotatable Bonds 80.0

Heavy Atoms 169.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414892 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetShigella sonnei ATTC 25931

Activity0.004 μM

MethodMIC

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