Peptide Database

Peptide NameGambicin

Function Ontology

—

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC150H236N46O45S4

DescriptionStandard

        APTCARCKSIGARYCGYGYLNRKGVSCDGQVSF
    

Molecular Weight3532.02 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1137

GRAVY Index-0.23

Hydrophobic Moment 0.38

Boman Index-0.05

Instability Index13.82

Aliphatic Index 50.30

Aromaticity 0.1212

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1488.56

LogP -19.13

H-bond Donors 58.0

H-bond Acceptors 53.0

Rotatable Bonds 113.0

Heavy Atoms 245.0

Ring Count 5.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0214015 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)