Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC846H1321N225O235S8

DescriptionStandard

        MPKLPAPLRKKLIALVLAGAGTFTIATHYTGYWEGKENTTYIDPTGTPTICYGHTGPDVKPGMTKTDEECLELLEKDMKWAFAAIDRHVQVPLTRGQTVALASWIFWAGETNFRNSTLLRLINAGQMPASCKQYIRWIYSKGVKLPGLEARRSADEWLCRYDLPKV
    

Molecular Weight18660.43 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0285

GRAVY Index-0.26

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index33.33

Aliphatic Index 82.35

Aromaticity 0.1024

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7326.21

LogP -64.33

H-bond Donors 260.0

H-bond Acceptors 251.0

Rotatable Bonds 601.0

Heavy Atoms 1314.0

Ring Count 37.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028842 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0252236 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella sonnei [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase