Peptide Database

Peptide NameTemporin-SN1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC106H161N21O21

DescriptionStandard

        FFPFLLGALGSLLPKIFGK
    

Molecular Weight2065.54 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0925

GRAVY Index1.24

Hydrophobic Moment 0.50

Boman Index0.56

Instability Index26.48

Aliphatic Index 128.42

Aromaticity 0.2105

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 641.81

LogP 0.55

H-bond Donors 21.0

H-bond Acceptors 23.0

Rotatable Bonds 64.0

Heavy Atoms 148.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099402 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetNocardia asteroides 201118

Activity6.3 μM

MethodMIC

RECORD: Rec_0186360 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus ATCC 25923

Activity12.5 μM

MethodMIC

RECORD: Rec_0273333 VERIFIED: NO

Provenance & Taxonomy

OrganismHylarana maosuoensis [Animal]; Hylarana spinulosa [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant

RECORD: Rec_0314746 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity200 μM

MethodHemolysis

RECORD: Rec_0342068 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetEnterococcus faecalis 981

Activity25 μM

MethodMIC