Peptide Database

Peptide NamePGIP_PYRCO

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length330 amino acids

Chemical FormulaC1650H2581N423O488S11

DescriptionStandard

        FHKQPNLTGPIQPAIAKLKGLKSLRLSWTNLSGSVPDFLSQLKNLTFLDLHNQLSGNIPTSFAQMDFTSIDLSRNKLEGDASVIFGLNKTTQIVDLSRNLIPVGGKLQSFDEYSYFHNRCLCGAPLPSCKLEFNLSKVEFPTSLTSLDINHNKIYGSIPVEFTQLNFQFLNVSYNRLCGQMELKFSTFLSLTLLFSSVLNPALSDLCNPDDKKVLLQIKKAFGDPYVLASSFNNLTGAIPSSLSELPNLGALRLDRNKLTGHIPISFGQFIGNVPDLYLSWKSDTDCCDWYCVTCDSTTNRINSLTIFAGQVSGQIPALVGDLPYLETLE
    

Molecular Weight36504.40 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-1.87

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0057

GRAVY Index-0.01

Hydrophobic Moment 0.61

Boman Index0.11

Instability Index29.07

Aliphatic Index 98.67

Aromaticity 0.0970

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28920.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350637 VERIFIED: YES

Provenance & Taxonomy

OrganismPyrus communis [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme