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MYP_162018
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Basic Information
KLW peptide [L9,13Nala]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKKLLKKXLKLXKKLLK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315719 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer
A549
75.5 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0320304 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 9,13
Bio-Activity Profile
Antimicrobial Antibacterial
A549 human lung carcinoma cells
75.5 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0370965 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 9,13
Bio-Activity Profile
Antimicrobial Antibacterial
SK-MEL-2 human melanoma cells
38.7 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0380377 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 9,13
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa KCTC 1637
2 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0393170 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
a=Nala (Ala-peptoid)
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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