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MYP_162010
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Basic Information
Turgencin B Mox1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
35 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIKEXLCNMACAQTVCKKSGGPLCDTCQAACKALG
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072381 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=MET-OXD
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
50 μM
IC50
PaperPubMed PMID: 31940927 PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0084965 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=MET-OXD
Bio-Activity Profile
Antimicrobial Anticancer
A2058
27.4 μM
IC50
PaperPubMed PMID: 31940927 PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0111827 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>50.0 μM
IC50
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0166810 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
25 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0177631 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
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