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MYP_161999
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Basic Information
Aerucyclamide C
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
6 amino acids
C24H44N6O8S2
Standard
Sequence
ITGCIC
Physicochemical Analysis
608.77 Da
5.51
-0.26
-0.49
-0.0433
2.15
0.34
0.63
-5.82
130.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
229.05
-2.21
10.0
10.0
18.0
40.0
0.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012083 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei rhodesiense STIB 900 (blood stage form)
9.2 μM
IC50; Alamar Blue assay
PMID18973386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18973386/
RECORD: Rec_0019791 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum K1
2.3 μM
IC50; [3H] Hypoxanthine incorporation assay
PMID18973386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18973386/
RECORD: Rec_0149795 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei rhodesiense STIB 900 (blood stage form)
50.1 μM
IC50; Alamar Blue assay
PMID18973386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18973386/
RECORD: Rec_0189556 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 0.0%, E 0.0%, T 33.3%, C 66.7% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Antitrypanosomal
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0303798 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum K1
6.3 μM
IC50; [3H] Hypoxanthine incorporation assay
PMID18973386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18973386/