Peptide Database

Peptide NameSLAY-screened peptide P2615

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC100H136N24O29S2

DescriptionStandard

        CSHTWFVDITIFHCSDFSG
    

Molecular Weight2202.42 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.08

Net Charge (pH 7.4) -2.42

Charge Density (pH 7.0) -0.1096

GRAVY Index0.43

Hydrophobic Moment 0.16

Boman Index0.32

Instability Index-14.28

Aliphatic Index 56.32

Aromaticity 0.2105

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 836.02

LogP -7.56

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 65.0

Heavy Atoms 155.0

Ring Count 7.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124858 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/