Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC192H313N61O46S6

DescriptionStandard

        IRNPFTCVRSGAICHPGFCPRRYKHIGVCGVSAIKCCKKP
    

Molecular Weight4404.31 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.47

Charge Density (pH 7.0) 0.1968

GRAVY Index-0.01

Hydrophobic Moment 0.61

Boman Index-0.03

Instability Index53.68

Aliphatic Index 65.75

Aromaticity 0.0750

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1696.11

LogP -17.20

H-bond Donors 66.0

H-bond Acceptors 62.0

Rotatable Bonds 139.0

Heavy Atoms 305.0

Ring Count 9.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096794 VERIFIED: YES

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)