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MYP_161892
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
35 amino acids
C172H279N43O61
Standard
Sequence
PNDITLNNSVALDPIDISIELNKAKSDLEESKEWI
Physicochemical Analysis
3925.31 Da
4.07
-5.03
-5.10
-0.1437
-0.46
0.40
-0.01
39.56
114.29
0.0286
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1695.70
-16.76
56.0
56.0
134.0
276.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040600 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 48.6%, E 0.0%, T 5.7%, C 45.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0190715 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 8700906 PMID8700906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8700906/
RECORD: Rec_0202408 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-Influenza virus Entry inhibition
Human parainfluenza virus type 3 (HPIV-3) | HEp-2 cells
25.48 μM
EC50
Mammalian: >20 h; Yeast: >20 h; E. coli: ?
PaperPeptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion. | Lambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr. | Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2186-91. | DOI:10.1073/pnas.93.5.2186 | PMID:8700906 PMID8700906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8700906/
RECORD: Rec_0321211 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 8700906 PMID8700906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8700906/
RECORD: Rec_0331793 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
Human parainfluenza virus type 3(HPIV-3):protection of HEp2 cell from viral cytopathic effect(CPE)
100 μg/mL
EC50
PaperPubMed PMID: 8700906 PMID8700906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8700906/
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