Peptide Database

Peptide NameSLAY-screened peptide P242

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC90H129N23O21S

DescriptionStandard

        PPGGYHCDLYFLILRH
    

Molecular Weight1901.19 Da

Isoelectric Point (pI)7.27

Net Charge (pH 7.0)0.12

Net Charge (pH 7.4) -0.05

Charge Density (pH 7.0) 0.0076

GRAVY Index0.01

Hydrophobic Moment 0.33

Boman Index0.22

Instability Index79.68

Aliphatic Index 97.50

Aromaticity 0.1875

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 674.06

LogP -2.21

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 55.0

Heavy Atoms 135.0

Ring Count 7.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0259542 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/