Peptide Database

Peptide NameIsracidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC120H190N38O33

DescriptionStandard

        RPKHPINHQGLSPEVPNENLLRF
    

Molecular Weight2693.03 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0408

GRAVY Index-1.09

Hydrophobic Moment 0.37

Boman Index-0.19

Instability Index60.10

Aliphatic Index 80.43

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1142.73

LogP -11.00

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 84.0

Heavy Atoms 191.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361853 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)