Peptide Database

Peptide Nametryptophan-modified porcine lactoferricin (LFP W8)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC87H139N31O21S

DescriptionStandard

        SKCRQWQWKIRRTNP
    

Molecular Weight1987.29 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)4.45

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.2965

GRAVY Index-1.98

Hydrophobic Moment 0.60

Boman Index-0.66

Instability Index42.76

Aliphatic Index 26.00

Aromaticity 0.1333

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.98

LogP -9.06

H-bond Donors 34.0

H-bond Acceptors 27.0

Rotatable Bonds 65.0

Heavy Atoms 140.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062549 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyLactoferricin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0266238 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLactoferricin

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity219 μM

MethodMIC

RECORD: Rec_0320303 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity500 μM

MethodMIC

RECORD: Rec_0368832 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLactoferricin

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity500 μM

MethodMIC

RECORD: Rec_0413009 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 25922

Activity219 μM

MethodMIC