Peptide Database

Peptide NameCyclotide protein Mra23 (Fragment)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC444H741N115O139S7

DescriptionStandard

        LATFEKDVITAETIQAVIKRTAPLSNIMLEGDAINALLTSKTVISKTVLEEAFLKTDATNGVIPCGESCVFIPCISSVLGCSCKNKVCYRNSLVN
    

Molecular Weight10138.78 Da

Isoelectric Point (pI)6.38

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0030

GRAVY Index0.42

Hydrophobic Moment 0.54

Boman Index0.16

Instability Index28.01

Aliphatic Index 109.79

Aromaticity 0.0421

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4079.76

LogP -43.16

H-bond Donors 146.0

H-bond Acceptors 146.0

Rotatable Bonds 340.0

Heavy Atoms 705.0

Ring Count 7.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143929 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0410157 VERIFIED: NO

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

ConfigBackbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial