Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC997H1567N255O289S9

DescriptionStandard

        MALHILELNTSGVFYPLDNLTDPPFLPVPFALPERHDSMLYVGISEFFFKSASFAYFTSGAFNVTLSMKEISNHLVQNSQGLGNVLSRIAEIYILSQPFMVRVMATEPPVISLQPGSFTLDIPASMVLLAQTENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVGIQALRVPCHGKNDNFPI
    

Molecular Weight22038.23 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-5.14

Net Charge (pH 7.4) -5.62

Charge Density (pH 7.0) -0.0256

GRAVY Index0.33

Hydrophobic Moment 0.63

Boman Index0.20

Instability Index50.24

Aliphatic Index 104.73

Aromaticity 0.0896

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116299 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii (Weddell seal) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria