Peptide Database

Peptide NameConotoxin Cl6.10

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC141H219N39O38S6

DescriptionStandard

        TRGCKTKGTWCWASRECCLKDCLFVCVY
    

Molecular Weight3260.88 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.34

Net Charge (pH 7.4) 2.05

Charge Density (pH 7.0) 0.0835

GRAVY Index0.04

Hydrophobic Moment 0.29

Boman Index-0.03

Instability Index26.18

Aliphatic Index 52.14

Aromaticity 0.1429

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1258.21

LogP -11.22

H-bond Donors 53.0

H-bond Acceptors 47.0

Rotatable Bonds 104.0

Heavy Atoms 224.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224159 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0339298 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 57.1%, C 42.9% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic