Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza

Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV cross

Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV ▸ Anti-HPIV3 cross

Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC162H285N49O54

DescriptionStandard

        ARSDIEKLKEAIRDTNKAVQSVQSSIGNLIVAIKS
    

Molecular Weight3783.29 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.60

Charge Density (pH 7.0) 0.0514

GRAVY Index-0.22

Hydrophobic Moment 0.71

Boman Index-0.10

Instability Index51.48

Aliphatic Index 114.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1723.54

LogP -20.77

H-bond Donors 60.0

H-bond Acceptors 56.0

Rotatable Bonds 136.0

Heavy Atoms 265.0

Ring Count 0.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281603 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman parainfluenza virus 3 [Virus]

FamilyVirus-derived peptide

Tax ID11216;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHuman parainfluenza virus type 3 (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

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