Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC378H611N101O102S10

DescriptionStandard

        MKFLLILTITLLLAQVTPAMKCWNKLGRCRETCEQNEVFYIMCKNEAMCCVSPKHLPAETESSNIAGRWRIFVV
    

Molecular Weight8523.16 Da

Isoelectric Point (pI)8.63

Net Charge (pH 7.0)2.54

Net Charge (pH 7.4) 2.17

Charge Density (pH 7.0) 0.0343

GRAVY Index0.22

Hydrophobic Moment 0.72

Boman Index0.09

Instability Index58.44

Aliphatic Index 94.86

Aromaticity 0.0811

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3263.62

LogP -24.97

H-bond Donors 119.0

H-bond Acceptors 116.0

Rotatable Bonds 283.0

Heavy Atoms 591.0

Ring Count 12.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015625 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0113201 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin